Medical Laboratory science
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Browsing Medical Laboratory science by Subject "Master Thesis"
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- ItemAssessment of Patient Safety Culture in the Palestinian Hospital Pharmacies(AL-Quds University, 2011) وفاء جمال حسن الزغاري; Wafa Jamal Hassan Zaghari; معتصم حمدان; Hussein Hallak; Ali ShaarBackground: Patient safety culture assessment in pharmacies is increasing largely worldwide, many tools that were used to assess patient safety culture at the hospital settings as a whole are now adapted to be used for pharmacies. One of the most commonly used and rigorously validated tools to measure patient safety culture is the Safety Attitudes Questionnaire (SAQ). The tool consists of 30 items that cover six safety culture domains. The intention of this research is to map the patient safety culture in the Palestinian hospital pharmacies, this will be achieved through measuring and analyzing the patient safety culture domains there, understanding factors influencing safety culture and examine variations between different hospital pharmacies. This assessment helps in determining safety culture domains that are considered as areas of strength, and safety culture domains that are considered as areas of weakness for each hospital pharmacy. Mapping patient safety culture in hospital pharmacies will end up by directing each hospital pharmacy to improve areas of weakness effectively and efficiently. Purpose: To assess patient safety culture in the Palestinian hospital pharmacies, and to assess the association of hospitals and respondents characteristics with patient safety culture. Methods: A cross-sectional design was used. The English version of the SAQ was translated and adapted to the Palestinian context. The survey was carried out in (28) Palestinian hospitals in the West Bank and East Jerusalem. All pharmacist assistants, pharmacist, and clinical pharmacists in these hospitals were targeted, estimated to 115 personnel. Items mean and scale scores were calculated. Then a composite score equivalent to the arithmetic mean of the scale scores were also calculated. In order to identify areas of strength and areas for potential improvement, the percentages of positive responses for the survey domains and items were calculated. Univariate analysis was used to test associations between composite patient safety scores and different respondent and hospital characteristics. viii Findings: 73 persons participated in the study, response rate was 68.8%. Females were 66.7%, 51% were pharmacist or clinical pharmacist, and 84.7% were with experience ≥ 5 years in profession. Two SAQ domains, job satisfaction and working conditions, were identified as areas of strength and received ≥75% of positive responses. Patient safety level was graded as “accepted” by (50%) of the respondents and none gave their pharmacy a “Poor” or “Failing” grade. Event reporting was very low, (66%) of the respondents didn’t report any event in the past year. In regard to the associations between safety culture domains scores with participants and hospital characteristics, the association was statistically significant (P<0.05) in regard to hospital ownership with the teamwork climate (P=0.02), perception of management (P=0.03), job satisfaction (P=0.001), and working conditions (P=0.02) and all in favor of the private and NGO hospitals. Participants working in hospitals sized <50 beds were more positive towards perception of management climate than their counterparts in larger sized hospitals (P=0.031). The overall safety score was significantly associated only with the hospital ownership (P=0.002) in favor of the private and NGO hospitals. No statistically significant associations were found between safety culture domains and the participant’s age, gender, years of experience in profession and hospital, level of education, working hours, and job title. The safety culture domain scores varied largely among different hospital pharmacies. None of the six domains were positive for four hospitals, twelve hospitals have negative total safety score and the best result was having five positive safety domains and a positive total safety score and this result was achieved only by two hospitals. Conclusions: Safety culture assessment results revealed areas for potential improvement in Palestinian hospital pharmacies. Hospitals need to formulate specific patient safety culture interventions to address these weaknesses
- ItemCorrelation between protease activated receptor (part1) polymorphism and recurrent abortion in Palestine(AL-Quds University, 2010-08-07) مرفت محمود سعيد ابوغزاله; MIRVAT MAHMOUD SAID ABU-GHAZALEH; زيدون صلاح; محمود سرور
- Item“Identification of immunoreactive Toxoplasma gondii epitopes selected by high antibody titer positive human sera suitable for immunodiagnostic techniques”(AL-Quds University, 2016-12-22) دينا نبيل خليل زيغان; Dina Nabil Khalil Zighan; إبراهيم عباسي; د. رسمي أبو حلو; د. سمير برغوثي; د. شيفاء العملةToxoplasma gondii is a coccidian obligatory intracellular protozoan parasite that utilizes cats as a definitive host and it is the causative agent of the toxoplasmosis (Abu-Madi, Behnke et al. 2008). The parasite affect about 30% of human population and it is considered a major zoonotic disease. (Chunlei Sua, Zhou et al. 2012; R. Edelhofer 2010) The disease is endemic in many countries in the world including Europe, United States and Mediterranean regions. The present study was conducted to identify immunoreactive Toxoplasma gondii epitopes using M13 phage display library for identifying peptides that mimic Toxoplasma gondii antigens. Phage display was done by plaque assay in 12 amino acid peptide phage library. For phage screening purposes; sera were collected from Toxoplasma gondii infected pregnant women, high antibody titer sera were pooled from different patients after screening for anti-Toxoplasma crude antigens by Modified Agglutination Test (MAT). By the aid of the high antibody titer Toxoplasma gondii pooled sera, three screening cycles of M13 phage display library, (12 amino acids peptides) were achieved. In the third screening cycle; 329 reactive plaques were obtained, 138 plaques that gave the strongest signals with pooled sera were selected for further analysis. Reactive peptides were isolated and sub-cloned in recombinant expression plasmid and were used in dot-ELISA to screen the selected M13 phage clones with pooled sera. ELISA test was also carried out to detect Toxoplasma infected individuals were identified. Phage Dot-Blot assay standardized for the confirmation of reactivity selected M13 phage clones with Toxoplasma gondii high antibody titer pooled sera and ELISA Assay revealed reactivity between selected amplified phages and some collected sera of Toxoplasma gondii infected individuals. The DNA coding the 12 amino acid peptide fused with the PIII M13 phage gene was amplified using specific primers flanking the peptide designed based on the PIII gene. DNA sequence was determined for 24 different clones, followed by bioinformatics DNA analysis by means of DNA alignment and BLAST search analysis. From the 24 sequenced peptides, 19 selected peptide clones represent the selected M13 phages showed no direct similarity to Toxoplasma gondii parasite DNA genomic sequences. So, due to that we was searching on amino acids sequence for the selected M13 phages through BLAST program. Data analysis showed a cross-reactivity between the selected M13 phages and anti-Toxoplasma pooled sera; which the sequences represent the selected M13 phages related to protozoan parasites such as Plasmodium knowlesi and Plasmodium fragile. These protozoan parasites are closely related to Toxoplasma family (Sarcocystidae). The selected M13 phage clones were pooled and tested for their reactivity against pooled anti-Toxoplasma sera in dot-blot and ELISA format. The obtained results showed specific interaction that need further studies and evaluation for the use of these phages in future Toxoplasma diagnosis.
- Itemاستخلاص شامل وفحص النشاط الحيوي ضد الميكروبات لنبتة ببيليريوم سبوفاتوم: عضو من النباتات الفلسطينية(AL-Quds University, 2016-05-14) ايه علي أحمد القاضي; aya ali ahmad Ghanayem; محمود ابو حديد; Hateim Eideh; Nidal Jaradat
- Itemالاختلافات الوراثية في التسلسلات الجينية لمستقبلات البيورينرجك- P2Y12 بين الفلسطينيين والسويديين والكونغوليين.(AL-Quds University, 2017-11-18) محمد يوسف سعيد عسعيس; MOHAMMED YOUSEF SAED ASEES; رانية أبو سير; Dr. Camilla Hesse; Khalid Younis; Majdi Dwekat
- Itemالأخطاء النحوية والإملائية الشائعة لدى طلبة الصف الأول الثانوي في مديرية تربية جنوب الخليل, أسبابها وطرق علاجها(AL-Quds University, 2014-02-18) احمد محمد خالد جبرين; Ahmad M. K. Jebreen; أحمد فهيم جبر; مشهور حبازي; ياسر الملاح
- Itemالأستعمال الأمثل لمياه الري وذلك من حيث الجودة والكمية اللازمة لنمو خضار البندورة في منطقة أريحا.(AL-Quds University, 2008-05-10) ناجح احمد عيسى غياضه; Najeh Ahmad Issa Ghayadeh; عامر مرعي; لا يوجد
- Itemالتصنيف الوراثي لأصناف الستريبتومايسيز باستخدام التحليل السلسلي لعديد المورثات(AL-Quds University, 2013-01-06) محمد احمد محمد قادي; mohammad ahmad mohammad qadi; سمير البرغوثي; د. ابراهيم العباسي Dr. Ibrahim Abbasi; د. وليد الباشا Dr. Walid Basha
- Itemالتصوير الطبقي للدماغ باستخدام جرعة شعاعية منخفضة ,دراسة مقارنة مع خوارزمية تحسين التباين(AL-Quds University, 2020-01-21) حمزه محمود عبد الرحيم العرجه; Hamza Mahmud AbdAlraheem Arjah; محمد حجوج; Adnan Lahham; Nader Sarhan
- Itemالتعرف على المعلمات السطحية لطفيل الليشمانيا من خلال استخدام مصل المصابين ذو التركيز العالي بالمضادات(AL-Quds University, 2012-05-16) نسرين سعيد عطا القاضي; NISREEN SAEID ATA ALQADI; ابراهيم عباسي; Sameer Barghouthy; Khaldoun Nijem
- Itemالتعرف على الوصف الجزيئي لفيروس التهاب الكبد الفيروسي البشري (أ) في عينات المصل من المرضى الفلسطينيين الذين يعانون من أعراض سريرية لالتهاب الكبد الفيروسي(AL-Quds University, 2017-12-17) حياه سميح احمد قراقع; Hayah Samih Ahmad Qaraqe; رسمي ابو الحلو; Sameer A.Barghouthi; Kamal Dumaidi
- Itemالتوصيف الجزيئي لنقص نازعة الهيدروجين من الجلوكوز 6 فوسفات في الشعب الفلسطيني في الضفة الغربية – فلسطين(AL-Quds University, 2016-08-24) ايمان وليد طالب ابوزاهريه; Eman Walid Talib Abuzahriyeh; محمود سرور; رانية ابو سير; فكري سمامره
- Itemالتوصيف الجزيئي واختبار أنماط الحساسية للمضادات الحيوية لبكتيريا العنقودية الذهبية المقاومة للميثيسيلين في فلسطين(AL-Quds University, 2018-05-05) عطاف سليمان ابراهيم هادية; ETAF SLIMAN IBRAHEEM HADYEH; كفاية عزمي; Dina Bitar; Adham Abu-Taha
- Itemالتوصيف الجزيئي والمضادات الحيوية لبكتيريا الزائفة الزنجارية (عصية القيح الأزرق) المعزولة من العدوى بعد العمليات الجراحية(AL-Quds University, 2016-12-22) هبه ناجح ياسين ملحم; Hiba Najeh Yaseen Milhem; حاتم عيده; Dr. Rasmi Al-Helo; Dr. Galeb Adwan
- Itemالحوسبة الشبكية لأجهزة الحواسيب الشخصية في مؤسسات التعليم العالي(AL-Quds University, 2013-06-15) بدر احمد بدر الاجرب; badir ahmad badir ajrab; لبيب عرفة; أحمد القطب; محمد الدشت
- Itemالسلوك الفيزيائي والكيميائي لخليط من خوافض التوتر السطحي اللاأيونيه(AL-Quds University, 2005-05-22) وائل ضامن السيد صلاح الدين; Wail Damin Al-sayyd Salah Al-diyn; منذر فنون; Mohammed Abul Haj; Alfred Aded Rabbo
- Itemالعلاقة بين بكتيريا الهليكوباكتر بيلوري و نوع فصيلة الدم و قدرة الشخص الإفرازية في فلسطين(AL-Quds University, 2013-06-01) علا طلال عبد الله كرمي; Ola Talal AbdAllah Karmi; محمود سرور; سمير البرغوثي; خالد يونس; جوني عامر
- Itemالعلاقه بين تعدد الاشكال الجيني للانترلوكينات (Interleukins) و الاجهاض المتكرر غير المبرر بين نساء الضفه الغربيه.(AL-Quds University, 2018-05-08) نفين نظام عرفات صب لبن; Niveen Nizam Arafat Sublban; رسمي ابو الحلو; Hatem Eideh; Fekri Samarah
- Itemالعلامات الجينية ذات التغير الطبيعي في سلسلة الحامض النووي الرايبوزي منزوع الأكسجين (DNA) في الجينين (MTHFR &VDR;) بين النساء الفلسطينيات المصابات بهشاشة العظام والسليمات في محافظة بيت لحم(AL-Quds University, 2005-06-21) رهام وليد سليم سموم; Riham Walid Salim Smoom; هشام درويش; Gassan Baaloosha; Elias Saba
- Itemالقيمة التنبؤية للتصوير الطبقي المقطعي والتصوير التلفزيوني في تحديد التهاب الزائدة الدودية(AL-Quds University, 2020-01-21) أحمد عبد الرحمن محمد حسين; Ahmad Abed Alrahman Mohammad Hussein; Mohammad Hjouj; Mohammed Maree; Nafez Sarhan