(Al-Quds University - Deanship of Scientific Research, 2023-05-16) Raghad Al-Shareef; Dania Ewadeh; Mariam Shehada; Ahmad Salhab; Mohamad Sleimeih; Ashraf Abdeen; Rozan Attili
Background: Thrombophilia is abnormal blood coagulation that leads to an increased risk of blood tendency to clot. Genetic factors tested as a whole panel consist of seven genetic abnormalities: Factor V Leiden, Factor V, Prothrombin (Factor II), Beta Fibrinogen, Factor 8, MTHFR (C677T), MTHFR (A1298C), and four risk factors: Human Platelet Antigen, Angiotensin-converting enzyme (ACE), Glycoprotein IIIa (GP IIIa) and Plasminogen Activator Inhibitor-1 (PAI-1). In some cases protein c, protein s and Antithrombin may be added.