Vol 5 No.1

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https://dspace.alquds.edu/handle/20.500.12213/9348

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    Antidepressants: New Hypothetical Interactions to Increase Their Efficiency
    (Deanship of Research/ Al-Quds University, 2024-04-01) Hanan Atari; Ghadeer Jamal; Dena Jaffal; Noor Alhalaby; Rayhana Aljana Jboor; Mohammad Qabajah
    Depression is a prevalent disorder that stems from an imbalance in brain chemistry, particularly involving neurotransmitters. It is commonly treated with antidepressants, such as Selective Serotonin Reuptake Inhibitors (SSRIs), which work by inhibiting the reuptake of serotonin. Paroxetine is one of the most commonly used SSRIs; however, it is associated with side effects on both thyroid and sex hormones. The objective of this study is to identify an alternative compound or drug to paroxetine that offers fewer side effects.
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    Assessing the Knowledge and Risk Awareness about over-the-counter (OTC) Supplements use for Children Aged 2-10 Years in Bethlehem City: Cross Sectional Study
    (Deanship of Research/ Al-Quds University, 2024-04-01) Anaheed Taqatqah; Doaa Mujahed; Sabri Saghir
    The increasing global demand for over-the-counter (OTC) supplements for children without real medical needs or prescriptions is a topic of debate, raising questions about their necessity and the extent to which they are used. Some studies support their use, while others are against it. However, there is a lack of similar studies regarding their use in Palestine.
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    Assessment of Antioxidant, Antimicrobial, and Anticancer Activity of Olea europaea Leaves Extracts and Its Effects on Apoptotic Genes
    (Deanship of Research/ Al-Quds University, 2024-04-01) Zain Wael Shweiky; Mahmoud Khalid
    The olive tree (Olea europaea) is a rich source of phenolic compounds, known for their health benefits. These compounds, particularly abundant in Palestinian olive leaves, have been shown to possess antioxidant and antimicrobial properties. This study explores the potential of olive leaf extracts to target cancer by investigating their effects on genes involved in the critical process of apoptosis, or programmed cell death.
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    Assessment of Mothers' Awareness of Sudden Infant Death Syndrome and Safe Infant Sleep Practices in Palestine
    (Deanship of Research/ Al-Quds University, 2024-04-01) Inas Yaghmour; Hadeel Shamasna; Ghayda Hijazi; Zeinab Shalan; Omar Almahmoud
    One of the major public health mysteries around the world is a subcategory of infant sleep- related deaths of unknown etiology termed Sudden Infant Death Syndrome (SIDS) which is a common leading cause of infant mortality worldwide and targets infants under a year of age while sleeping. Sleep environment plays a significant role in the risk of SIDS, otherwise mothers' actions for creating safe infant sleep practices plays a protective role in reducing SIDS occurrence. The knowledge gap centered on SIDS is not adequately researched or investigated in Palestine. Correspondingly, the study aims to assess mothers' awareness of SIDS and safe infant sleep practices.
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    Assessment of Satisfaction and Associated Factors among Postpartum Cesarean Mothers in Private Hospitals in Nablus
    (Deanship of Research/ Al-Quds University, 2024-04-01) Dina Abusharbak; Nabil Nicola; Sojoud Mahammed; Mohammad Tayeh; Osama Asbah; Shurouq Qadous
    Understanding maternal satisfaction is essential to identify factors and interventions that directly affect the childbirth experience, especially among mothers who have undergone a cesarean section.
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    Awareness, Knowledge and Practices of Laser Hair Removal (LHR) among people visiting special clinic in Palestine: Cross sectional study
    (Deanship of Research/ Al-Quds University, 2024-04-01) Yasmin Alsheikh; Shahd Abu Rass; Sawsan Salameh
    Excess body and facial hair, particularly in women, can cause substantial psychological and social distress, including emotional strain, anxiety, and depression, as well as lowered self-esteem and academic and occupational performance. Shaving, waxing, plucking, and depilatory treatments are among methods for eliminating unwanted hair. However, these methods are time-consuming, unsuccessful, and may cause pain. In addition, they can cause skin irritation, infection, allergic or irritant dermatitis, and scarring. Despite the well-known benefits of laser hair removal (LHR), there are many misconceptions and negative attitudes among the public. These include fear of pain, burns, scars, damage to the eyes and internal organs, skin cancer, and changes in skin tone and texture.
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    Basic Geriatric Knowledge and Awareness among Palestinian Physicians: A Cross Sectional study
    (Deanship of Research/ Al-Quds University, 2024-04-01) Oadi Shrateh; Jalal Al-Khateeb; Nicolas Elshatleh; Raghad Sweity; Rita Yacoub; Seham Madaka; Hussein Hallak
    As it is the trend worldwide, Palestine is expected to experience significant changes in demographics over the upcoming few decades, with the percentage of elderly people aged above 65 anticipated to increase in the years ahead. This necessitates concerted efforts to achieve a better understanding of geriatric care and to establish infrastructure of medical professionals and facilities qualified to deal with this vulnerable population. Given the lack of specialized training in geriatric care in medical schools and the absence of geriatric specialty programs in Palestine, assessing healthcare providers’ knowledge and awareness of normal aging and geriatric syndromes would be a very appropriate initial step to direct such efforts.
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    Beyond Medications: Understanding the Perspectives of Community Pharmacists on Non-pharmaceutical Products in Palestine
    (Deanship of Research/ Al-Quds University, 2024-04-01) Rafeef Jamal Al-Thwaib; Tasnim Yousef Mujahed; Rania Ghanem; Maher Khdour
    Non-pharmaceutical NP products are not classified as pharmaceuticals or medical devices, neither they include over-the-counter nor prescription drugs. Despite being highly consumable preparations intended for internal or external use by humans, NP products are found to be rapidly growing and distributed in pharmacies such as; skincare, hair care, oral, dental care and baby care products etc.
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    Bio Political Dynamism in Settler Colonialism: Environmental Violence as Genocide in Gaza after 2007
    (Deanship of Research/ Al-Quds University, 2024-04-01)
    The conflicts in Gaza have sparked a myriad of interrelated issues, spanning from humanitarian emergencies and economic turbulence to extensive devastation of infrastructure and casualties. My primary focus centers on pollution, particularly environmental pollution encompassing air, water, and landfill contamination, and its ramifications. This study aims to comprehend the aftermath of this ongoing genocide by juxtaposing them with previous wars, particularly those occurring after 2007, regarding environmental pollution and the potential for advancement.
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    Challenges of Machine Translation of English-Arabic Cultural Language Expressions: ChatGPT as a Case
    (Deanship of Research/ Al-Quds University, 2024-04-01) Layan Abu Hatab; Mahmoud Ahmad Abdel-Fattah-Ismail
    Translation is a complex and essential process that goes beyond word-for-word conversion. It involves transferring meaning between cultures, encompassing social, religious, and linguistic nuances. Observations about misunderstandings arising from a failure to understand the intention of a speaker is particularly relevant to the context of translation. This highlights the need to examine the efficiency of machine translation in achieving functional equivalence when translating cultural language expressions, as this poses critical challenges.
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    Chilean TRC: Truth-Telling and Gaining Democracy
    (Deanship of Research/ Al-Quds University, 2024-04-01) Ala'a Ahmad Mohammad Abhari; Zlata Bozac
    In 1990 a truth and reconciliation commission (TRC) was established after the military dictatorship under Augusto Pinochet’s regime between the period (1973-1990), where human rights were violated, and many victims struggled during the regime. After that dictatorial regime ended, there was democratic elections which made the new president at that time: Patricio Aylwin establish the TRC, and it was named the Rettig after its chairman; just six weeks after his inauguration as the new Chilean president, who made it clear that his prominent goal is to investigate human rights violations during the past through this TRC. As reported by Brahms, the Rettig had many aims, and the most crucial were: investigating gross human rights violations that occurred during the 17-years-long dictatorship, exploring the cases in which the victims were killed or disappeared, prosecute the perpetrators, and prevent the repetition of human rights abuses, and recommend reparations. This paper will explore the methods in which the Rettig investigated the cases during the military dictatorship, and will investigate some important concepts that challenged the TRC’s job or were interconnected with, and the outcomes and reparations of the TRC, which will help us in understanding the dramatic transition into democracy after the dictatorship in 1990. Therefore, the research question that will be examined in this research is: what were the utilized methods of investigation by the Chilean TRC and were they effective?
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    Circular Economy: The Silver Bullet to the Palestinian Solid Waste Problem
    (Deanship of Research/ Al-Quds University, 2024-04-01) Qais Ayasa; Sobhi Samour
    The research critically examines the feasibility of adopting a CE model to address the challenges of SWM in Palestine. It identifies the current waste management system as inefficient, with detrimental impacts on both the environment and the economy. The central thesis of the study is to assess whether a circular economy could be more effective than the existing LE, particularly in the context of a developing country like Palestine.
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    Consequences of COVID-19 in Adult Patients at least 10 Months after Infection in the West Bank
    (Deanship of Research/ Al-Quds University, 2024-04-01) Duha Doudin; Noor Halaseh; Tareq Jarrar; Atheer Shaheen; Eyad Jo'beh; Ahmad Abu Sa'da; Ahmad Abu Awwad; Peter Bael; Bayan Alqtishat; Hussein Hallak
    The COVID-19 pandemic has resulted in a global health disaster with significant rates of morbidity and mortality. Over 772 million people were infected and nearly seven million have lost their lives. The virus plagues the respiratory system mainly causing fever, dyspnea, and dry cough as initial symptoms. The long-term effects of COVID-19 are still unknown, particularly in the Middle East, so this study was conducted to determine the long-term consequences of COVID-19 on Palestinian people living in the West Bank.
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    Design a Novel Method to Cluster Data Based on an Angular Randomization Test
    (Deanship of Research/ Al-Quds University, 2024-04-01) Baneen Hussein Abd Zaid; Abeer Ali Naji; Kawthar Hataf Fazaa; Ahmed Jebur Ali
    Cluster analysis of amino acids poses a difficult task in the field of predicting protein function and structure. This research proposes a novel method that focuses on using the p-value obtained from an angular randomization test that evaluates the similarity of dihedral-angle distributions as the main measure for clustering.
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    Design and manufacturing of a Transcutaneous Electrical Stimulation System for Migraine Treatment
    (Deanship of Research/ Al-Quds University, 2024-04-01) Leen Ali; Auns Al-Neami
    Migraine is a complex disorder that characterized by recurrent episodes of headache most often unilateral and in some cases associated with visual or sensory symptoms that unfold over hours to days and disrupts the daily life of the patient and makes him lose his ability to focus.Experts estimate that 18.5% of the general population get migraine headaches. Women are about three times more likely than men to experience migraines, especially women between the ages of 15 and 55.
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    Detection of Acute Stroke Using the Alberta Stroke Program Early CT Score (ASPECTS)
    (Deanship of Research/ Al-Quds University, 2024-04-01) Hala Ahmad Othman Khateeb; Haneen Mohammad Terawi; Wafaa Shwiky; Nagham Salman; Alaa Abutair; Assel Natsheh; Ala' Thawabteh
    In 2022, cerebral strokes ranked fourth as the leading cause of death in the Palestinian Ministry of Health, accounting for 11% of all deaths. The Alberta Stroke Program Early CT Score (ASPECTS) is a quick, semi-quantitative way to assess ischemic lesions and predict prognosis in patients with ischemic stroke. It is a straightforward, reliable method for evaluating early ischemic changes in the blood supply region of the middle and posterior cerebral arteries. The primary basis for this strategy is the visual observation of doctors. However, the low inter-reader agreement could lead to mistakes in the final diagnosis because of the doctor's varying degrees of experience. To aid medical professionals in their diagnosis and assessment, this work proposes the use of non-contrast computed tomography (NCCT) as the basis for the ASPECTS technique of acute ischemic stroke.
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    Evaluation of Antibiotic Therapy and Clinical Outcomes for Community-acquired Pneumonia in Hospitalized Adults: A prospective cohort study in Palestine
    (Deanship of Research/ Al-Quds University, 2024-04-01) Haneen Mahmoud Nimer Habes; Samah Abuajamiah; Ghaidaa Manasrah; Mariam Brbarawi; Israa Sharabati; Baraa.M.Ayesh; Yousef M. Habes
    Community-acquired pneumonia (CAP) is considered as the most common infectious cause of death and the second most common cause of hospitalization in the United States. CAP is a major cause of antibiotics prescription and hospitalization worldwide, so rational prescribing of antibiotics needs to be paid attention. Data describing the actual management and effectiveness of several classes of antibiotics in treating CAP patients in Palestine are limited.
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    Exploring the Use of Complementary and Alternative Medicine for Treatment and Prevention of Flu
    (Deanship of Research/ Al-Quds University, 2024-04-01) Ahmad Ibrahim; Abdallah Zamareh; Naseem Hamdan; Dala Daraghmeh
    Complementary and Alternative Medicines (CAM) could be a viable option in treating influenza pandemics, especially as stockpiling antivirals can be expensive and developing effective vaccines for influenza is challenging due to frequent changes in virus antigenic structures, making it difficult for ongoing research. CAM practices and remedies are a promising and affordable option that prioritizes a holistic approach to health. Although the effectiveness of CAM can differ, their use is increasing globally. However, there is a lack of research on how CAM is used for influenza prevention and treatment among Palestinians.
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    Food Hygiene Practices in Food Restaurants
    (Deanship of Research/ Al-Quds University, 2024-04-01) Shereen Adeb Hroub; Enas Zaher Hroub; Wesam Mahmoud Sammar
    Food safety is a system that encompasses the handling, preparation, and storage of food in ways that prevent the transmission of contaminants. This is achieved through a series of routine procedures aimed at averting health risks and to avoid food spoilage. Food spoilage can lead to food poisoning, which is a common condition resulting from the consumption of contaminated food. Shawarma (cooked meat) also called shawarma, shawerma, and Kebab is one of the common fast-food meals consumed by most people. However, this meal may cause a health risk to the consumer due to its potential to contain harmful microorganisms, this is often a result of inadequate cooking processes and general hygiene practices.
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    Identification of Toxoplasma Gondii Epitopes Using Phage Display Libraries for Serodiagnostic Purposes
    (Deanship of Research/ Al-Quds University, 2024-04-01) Deena Sayes; Ibrahim Abbasi
    Toxoplasmosis is a parasitic disease caused by Toxoplasma gondii that can infect humans and animals. Currently, the diagnosis of toxoplasmosis can be performed through various methods, including serological and molecular methods. However, while molecular methods are highly sensitive and specific, they require highly specialized laboratory equipment and high BSL (biosafety levels), which may not be readily available in many settings. Moreover, molecular methods require the use of genetic material, which can pose a risk of infection for laboratory personnel. On the other hand, serological methods are more accessible and affordable, and they can detect the presence of antibodies against T. gondii, which indicates a past or current infection. Additionally, serological methods can identify specific T. gondii antigens or epitopes, which can be used to develop diagnostic tools without the need for live parasites. Thus, there is a need to explore the potential of serological methods for the diagnosis of toxoplasmosis and their potential applications in the development of safer and easier diagnostic tools. The identification of specific epitopes using phage display libraries can improve the specificity and sensitivity of diagnostic assays for T. gondii infection in cats and humans. Objectives: the research aims to identify specific epitopes that can be used in the diagnosis of Toxoplasma gondii infection using M13 phage display libraries, and then to analyze the sequences of the isolated phages using next generation DNA sequencing and bioinformatics tools.