Comparison of extraction yields, antioxidant, antimicrobial activity and concentration of main components of Olea europaea leaf samples at different seasons and of different areas in Palestine

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dc.contributor.authorHanania, Michel
dc.contributor.authorAbu Khairan, Rawan
dc.contributor.authorAl-Aaraj, Amira
dc.contributor.authorKayali, Ibrahim
dc.date.accessioned2019-11-06T10:58:51Z
dc.date.available2019-11-06T10:58:51Z
dc.date.issued2018-08-15
dc.description.abstractOlea europaea is widely cultivated tree for oil production in the Mediterranean area. The benefits of olive leaves refer to their vital polyphenols components. In this study, the optimum way for the extraction of olive leaves using Soxhlet extractor and various concentrations of ethanol as solvent was examined. In order to find the effect of environmental conditions on the extraction yield and chemical composition of olive leaves, phenolic components of olive leaf extract (Oleuropein and Rutin) were analyzed area-wise and seasonwise by a new and reliable RP-HPLC method. Extracts were screened for two pharmacological effects, namely antioxidant and antimicrobial activities. Thus, olive leaves were collected from three different areas in Palestine [south (Hebron), center (Beit Jala) and north (Tulkarm)] at two maturation stages [June 2014 (season 1) and October 2014 (season 2)]. Results showed that 75% EtOH was the best extracting solvent and season 2 gave higher yields of extraction. Beit Jala samples showed higher extracts than the two other areas with higher concentrations of Oleuropein, while Rutin was not detectable. Antioxidant activity was higher for untreated samples and samples of Hebron and Beit Jala had similar values. All samples showed good antimicrobial activity against Gram positive bacteria, while no inhibition was detected against Gram negative bacteria.en_US
dc.description.sponsorshipThis work was supported financially by an internal research grant from Bethlehem University. Authors are grateful to the Department of Biology at Bethlehem University for providing bacterial strains and helping in the antimicrobial tests.en_US
dc.identifier.citationTY - JOUR AU - Hanania, Michel AU - Abukhairan, Rawan AU - Al-Aaraj, Amira AU - Kayali, Ibrahim PY - 2018/01/01 SP - 253 EP - 262 T1 - Comparison of extraction yields, antioxidant, antimicrobial activity and concentration of main components of Olea europaea leaf samples at different seasons and of different areas in Palestine VL - 11 DO - 10.20902/IJPTR.2018.11307 JO - International Journal of PharmTech Research ER -en_US
dc.identifier.issn2455-9563
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/4857
dc.language.isoenen_US
dc.publisherSphinx Knowledge Houseen_US
dc.subjectOlive leafen_US
dc.subjectSoxhlet extractionen_US
dc.subjectOleuropeinen_US
dc.subjectRutinen_US
dc.subjectantimicrobial activityen_US
dc.titleComparison of extraction yields, antioxidant, antimicrobial activity and concentration of main components of Olea europaea leaf samples at different seasons and of different areas in Palestineen_US
dc.typeArticleen_US
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