Oxetane-containing metabolites: origin, structures, and biological activities

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dc.contributor.authorVil, Vera
dc.contributor.authorTerent’ev, Alexander O.
dc.contributor.authorAl Quntar, Abed Al Aziz
dc.contributor.authorGloriozova, Tatyana A.
dc.contributor.authorSavidov, Nick
dc.contributor.authorDembitsky, Valery M.
dc.date.accessioned2019-11-22T08:25:22Z
dc.date.available2019-11-22T08:25:22Z
dc.date.issued2019-01-04
dc.description.abstractCyclobutanes containing one oxygen atom in a molecule are called oxetane-containing compounds (OCC). More than 600 different OCC are found in nature; they are produced by microorganisms, and also found in marine invertebrates and algae. The greatest number of them is found in plants belonging to the genus Taxus. Oxetanes are high-energy oxygen-containing nonaromatic heterocycles that are of great interest as new potential pharmacophores with a significant spectrum of biological activities. The biological activity of OCC that is produced by bacteria and Actinomycetes demonstrates antineoplastic, antiviral (arbovirus), and antifungal activity with confidence an angiogenesis stimulator, respiratory analeptic, and antiallergic activity dominate with confidence from 81 to 99%.en_US
dc.identifier.citationVil, V., Terent’ev, A.O., Al Quntar, A.A.A. et al. Appl Microbiol Biotechnol (2019) 103: 2449. https://doi.org/10.1007/s00253-018-09576-zen_US
dc.identifier.issn1432-0614
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/4956
dc.language.isoenen_US
dc.publisherSpringer-Verlag GmbH Germanyen_US
dc.subjectOxetaneen_US
dc.subjectCyclobutaneen_US
dc.subjectMicroorganismsen_US
dc.subjectFungien_US
dc.subjectAlgaeen_US
dc.subjectInvertebratesen_US
dc.subjectPlanten_US
dc.subjectActivitiesen_US
dc.titleOxetane-containing metabolites: origin, structures, and biological activitiesen_US
dc.typeArticleen_US
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