Postpartum choriocarcinoma complicated by uterine perforation: A case report and literature review
| dc.contributor.author | Rayan R. Salahaldin | |
| dc.contributor.author | Mais E. Abubaker | |
| dc.contributor.author | Ghada M. Abdalqader | |
| dc.contributor.author | Anas R. Tuqan | |
| dc.contributor.author | Basel A. Zaben | |
| dc.contributor.author | Iba Barghouthi | |
| dc.date.accessioned | 2025-02-24T10:12:29Z | |
| dc.date.available | 2025-02-24T10:12:29Z | |
| dc.date.issued | 2025-02-22 | |
| dc.description.abstract | Choriocarcinoma is a rare, aggressive gestational trophoblastic disorder with metastatic potential, often presenting with abnormal bleeding and increasing levels of beta-human chorionic gonadotropin (b-hCG). Diagnosis is confirmed through histopathologic examination after curettage, and treatment typically involves stagedependent chemotherapy. This case report concerns a 25-year-old woman with heavy postpartum bleeding, later diagnosed with choriocarcinoma. Despite initial single-agent chemotherapy, disease progression led to uterine perforation and hemoperitoneum, requiring emergency surgery. Following recovery, multi-agent chemotherapy resolved her symptoms. Choriocarcinoma’s rarity and varied presentation make diagnosis challenging, with lung metastases common. Levels of b-hCG indicate treatment response, and prompt management combining chemotherapy, monitoring, and surgery is crucial for positive outcomes. | |
| dc.identifier.uri | https://dspace.alquds.edu/handle/20.500.12213/9734 | |
| dc.language.iso | en | |
| dc.title | Postpartum choriocarcinoma complicated by uterine perforation: A case report and literature review | |
| dc.type | Article |