Diet and Genetic Risk Factors of Colorectal Cancer in Palestine: A Case-Control Study

Simple item page
dc.contributor.authorGhrouz, Issa
dc.contributor.authorEl Sharif, Nuha
dc.date.accessioned2021-12-18T12:24:28Z
dc.date.available2021-12-18T12:24:28Z
dc.date.issued2021-12-08
dc.description.abstractTo add evidence to the limited data available on colorectal cancer (CRC) from Palestine, we examine the risk factors associated with CRC using a matched hospital-based case-control study. A structured questionnaire was used to collect data from 105 cases and 105 controls. A multivariable conditional regression model was used to adjust for the association between study factors and CRC risk. In the model, compared with controls, cases from villages were significantly less likely to have CRC (Adjusted Odds Ratio, AOR = 0.194); taking aspirin lowered the likelihood of CRC by 24%; and having a multiple birth sibling by 33%. Also, the likelihood of CRC was lowered significantly by consuming five servings of fruits/vegetables per week or more (5–6 servings: AOR = 0.21, 7–8 servings per week: AOR = 0.04). However, cases had a significantly higher likelihood of CRC if they consumed 2–4 servings of grilled red meat per week (AOR = 4.25); smoked (AOR = 4.38); had a sedentary lifestyle (AOR = 2.53); reported parental consanguinity (AOR = 3.88); or had a family history of cancer (AOR = 6.39). Our results confirmed the association between CRC and red meat intake and smoking, and proved that parental consanguinity and family history of cancer are also risk factors for CRC.en_US
dc.description.sponsorshipThe authors wish to thank all participants for their will- ingness to participate and the Ministry of Health teams for facilitating the study implementation. Also, the authors wish to express their gratitude to Al Quds University for funding this research.en_US
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/6502
dc.language.isoenen_US
dc.publisherTaylor & Francis Groupen_US
dc.titleDiet and Genetic Risk Factors of Colorectal Cancer in Palestine: A Case-Control Studyen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Diet and Genetic Risk Factors of Colorectal Cancer in Palestine A Case Control Study-1-1.pdf
Size:
774.88 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.61 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
AQU researchers publications