Antidepressants: New Hypothetical Interactions to Increase Their Efficiency
Date
2024-04-01
Authors
Hanan Atari
Ghadeer Jamal
Dena Jaffal
Noor Alhalaby
Rayhana Aljana Jboor
Mohammad Qabajah
Journal Title
Journal ISSN
Volume Title
Publisher
Deanship of Research/ Al-Quds University
Abstract
Depression is a prevalent disorder that stems from an imbalance in brain chemistry, particularly involving neurotransmitters. It is commonly treated with antidepressants, such as Selective Serotonin Reuptake Inhibitors (SSRIs), which work by inhibiting the reuptake of serotonin. Paroxetine is one of the most commonly used SSRIs; however, it is associated with side effects on both thyroid and sex hormones. The objective of this study is to identify an alternative compound or drug to paroxetine that offers fewer side effects.