• English
    • العربية
  • العربية 
    • English
    • العربية
  • دخول
عرض المادة 
  •   الرئيسية
  • AQU Research Network Clusters
  • AQU researchers publications
  • عرض المادة
  •   الرئيسية
  • AQU Research Network Clusters
  • AQU researchers publications
  • عرض المادة
JavaScript is disabled for your browser. Some features of this site may not work without it.

Preparation and characterization of carvedilolloaded poly(d,l) lactide nanoparticles/ microparticles as a sustained-release system

Thumbnail
عرض/افتح
Int J of polymeric materials and polymeric biomaterials 2017 Assali%2c M.pdf (1.007Mb)
التاريخ
2017-02-08
المؤلف
Assali, Mohyeddin
Zaid, Abdel Naser
Bani-Odeh, Majd
Faroun, Maryam
Muzaffar, Riham
Sawalha, Hassan
واصفات البيانات
عرض سجل المادة الكامل
الخلاصة
Carvedilol poly(D,L)-lactide nanoparticles/microparticles were prepared. The size and morphology of the developed particles were optimized to study the carvedilol release profile by studying the effect of organic solvents and polymer amount through atomic force microscopy analysis. Spherical particles were obtained with a minimum size of 125 nm in the case of acetone and a maximum size of 970 nm in the case of dichloromethane affording microparticles formation. The interaction was confirmed by differential scanning calorimeter and Fourier transform infrared. The in vitro release profile of the multicompartment system (pure carvedilol, loaded nanoparticles and microparticles) has shown a sustained release with Korsmeyer–Peppas with T lag model.
المكان (URI)
https://dspace.alquds.edu/handle/20.500.12213/5009
حاويات
  • AQU researchers publications [782]

DSpace software copyright © 2002-2016  DuraSpace
اتصل بنا | ارسال ملاحظة
Theme by 
Atmire NV
 

 

استعرض

جميع محتويات المستودعالمجموعات & الوحداتحسب تاريخ النشرالمؤلفونالعناوينالمواضيعهذه الوحدةحسب تاريخ النشرالمؤلفونالعناوينالمواضيع

حسابي

دخول تسجيل

DSpace software copyright © 2002-2016  DuraSpace
اتصل بنا | ارسال ملاحظة
Theme by 
Atmire NV