AMPLICON-BASED NGS FOR DETECTION AND GENOTYPING OF HERPESVIRUSES IN HEALTHY PALESTINIAN INDIVIDUALS IN SPECIFIC REGIONS IN PALESTINE

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dc.contributor.authorBushra Mahmoud Ismail Mahmoud
dc.contributor.authorAbed Almajeed Naseredden
dc.contributor.authorBushra Mahmoud Ismail Mahmoud
dc.date.accessioned2026-09-15T06:07:36Z
dc.date.available2026-09-15T06:07:36Z
dc.date.issued2026-05-12
dc.description.abstractHerpesviruses, including Cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus type 1 (HSV-1), and type 2 (HSV-2), are widespread and pose serious public health challenges due to their ability to persist in the body and spread easily. While diagnostic tools have improved over the years, commonly used methods like serological tests and PCR-based assays still have limitations. Next-generation sequencing (NGS) has opened a new era in viral diagnosis, allowing for the simultaneous detection of multiple viruses in a single test, thereby improving both speed and precision of results. In Palestine, there is a significant gap in research on herpesvirus prevalence and genotypes, and access to advanced molecular diagnostics such as NGS remains limited. Many local laboratories still rely on traditional methods, which may lead to underdiagnosis or misclassification of infections. Since herpesviruses can remain latent without causing symptoms, an NGS-based approach that screens for all herpesviruses in a single test could enhance detection while reducing costs. This study aims to investigate the prevalence and genetic diversity of herpesviruses among asymptomatic individuals, addressing a critical need for improved viral surveillance in the region.
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/10810
dc.language.isoen
dc.publisherDeanship of Scientific Research - Al-Quds University
dc.titleAMPLICON-BASED NGS FOR DETECTION AND GENOTYPING OF HERPESVIRUSES IN HEALTHY PALESTINIAN INDIVIDUALS IN SPECIFIC REGIONS IN PALESTINE
dc.typeArticle
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