Assessment of the antimicrobial and free radical scavenging activities of Moluccella spinosa, Helichrysum sanguineum, and Styrax officinalis folkloric medicinal plants from Palestine
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Date
2018-05-26
Authors
Jaradat, Nidal
Al‑Masri, Motasem
Naser Zaid, Abdel
Hussein, Fatima
Shadid, Khalid Ahmad
Al‑Rimawi, Fuad
Shayeb, Khaled
Sbeih, Afnan
Eid, Alia
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
The emergence of pathogenic microbes with increased resistance to established antibiotics provides a major incentive
for the discovery of new antimicrobial agents. Herbals may provide valuable solutions for this global problem. In addition,
the replacement of harmful synthetic antioxidants with natural ones may prevent various serious diseases. The present
investigation describes for the first time the antioxidant and antimicrobial activities of the aqueous and organic extracts of
Helichrysum sanguineum, Moluccella spinosa and Styrax officinalis plants aerial parts. The free radical scavenging activity
was estimated using the 2,2-diphenyl-1-picrylhydrazyl method, while the antimicrobial activity was evaluated against
selected microbial strains from American Type Culture Collection and clinical isolates such as Shigella sonnie, Staphylococcus
aureus, Enterococcuss feacium, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Epidermophyton floccosum
and Methicillin Resistant Staphylococcus aureus (MRSA) using minimum inhibitory concentration assay. A mixture
of phytochemical compounds was found in all of the studied plants extracts which also showed remarkable potentials of
antioxidant and antimicrobial activities. The current study provides initial data that justify the use and importance of these
plants in the Palestinian traditional medicine. In addition, it provides evidence that the aqueous and organic extracts of H.
sanguineum, M. spinosa and S. officinalis exhibited interesting antioxidant activity comparing with Trolox. Furthermore, the
organic extract of H. sanguineum strongly exhibited bacterial growth of S. aureus, E. faecium and MRSA which suggested
to be used as antibiotic alternative or as sufficient natural food preservative.
Description
Keywords
Helichrysum sanguineum , Moluccella spinosa , Styrax officinalis , Antibacterial , Antifungal , Antioxidant