Accelerations in the Lactonization of Trimethyl Lock Systems Aredue to Proximity Orientation and not to Strain Effects
| dc.contributor.author | Karaman, Rafik | |
| dc.date.accessioned | 2018-09-03T10:32:05Z | |
| dc.date.available | 2018-09-03T10:32:05Z | |
| dc.date.issued | 2009-02-10 | |
| dc.description.abstract | DFT at B3LYP/6-31G(d, p) and HF at 6-31G and AM1 semiempirical calculations of thermodynamc and kinetic parameters for the trimethyl lock system (an important enzyme model) indicate that the remarkable enhancement in the lactonizations is largely the result of a proximity orientation as opposed to the currently advanced strain effect. | en_US |
| dc.description.sponsorship | The author thanks the Karamans Co. and the German- Palestinian-Israeli fund agency for support of our hardware computational facilities. Special thanks go to Dr. Omar Deeb and Sherin Alfalah and Donia Karaman for support in computational software and technical assistance. His sincere appreciations are given to Professor Fred Menger (Emory University, Ga, USA) for helpful discussions. | en_US |
| dc.identifier.issn | 1875-6255 | |
| dc.identifier.uri | https://dspace.alquds.edu/handle/20.500.12213/804 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Hindawi Publishing Corporation | en_US |
| dc.title | Accelerations in the Lactonization of Trimethyl Lock Systems Aredue to Proximity Orientation and not to Strain Effects | en_US |
| dc.type | Article | en_US |