Identification of drug-related problems: a prospective study in two general hospitals

dc.contributor.authorJarab, Anan
dc.contributor.authorMukattash, Tareq
dc.contributor.authorHallak, Hussein
dc.contributor.authorAdas, Heba
dc.contributor.authorSamaro, Ekhlas
dc.contributor.authorKhdour, Maher
dc.date.accessioned2018-08-18T11:44:32Z
dc.date.available2018-08-18T11:44:32Z
dc.date.issued2012-11-04
dc.description.abstractDrug-related problems (DRPs) can reduce the potential clinical benefits of treatment with medicines and waste valuable resources. No previous studies were published to examine the nature and frequency of drug related problems among hospitalized patients in Palestinian hospitals. Methodology: Prospective observational study was conducted to report and record the natural and frequency of drug related problems in two general hospitals. Results: The study included 212 patients, 54.4 % female, with a mean age 62.2 (±10.6 SD). 88% of the patients were reported with one or more DRPs, with an average of 1.9 DRPs per patient were found. The most prevalent DRP was incorrect dosing regimen which was represented by (22.2%), followed by drug-drug interaction (19.4%), drugs need laboratory tests (15.2%). Ceftriaxone, warfarin, enoxapirin and dogixin were the drugs causing most frequent DRPs. The drug groups causing most DRPs were anti-infective agents, anti-thrombotic agents and non-steroidal anti-inflammatory agents. Once discovered, the majority of DRPs (71.6%) were accepted by the physicians and solved immediately, while 11.5 % of pharmacist advice was not approved. Multiple regression analysis indicated that the number of medications (RR 1.99; 95% CI 1.31-3.76) and the number of medical conditions (RR 1.81; 95% CI 1.11-3.13) independently predicted the number of DRPs. Conclusion: DRPs in general hospitals are frequent, serious and predictable. Most of the problems identified as DRPs by the pharmacists were accepted by the physicians and solved. Pharmacists in the hospital setting are well suited to identify and resolve DRPs.en_US
dc.description.sponsorshipDeclared none.en_US
dc.identifier.issn2212-3938
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/752
dc.language.isoen_USen_US
dc.publisherBentham Science Publishersen_US
dc.subjectDRPsen_US
dc.subjectPharmacist interventionen_US
dc.subjecthospital settingen_US
dc.subjectadverse drug reactionen_US
dc.subjectPalestineen_US
dc.titleIdentification of drug-related problems: a prospective study in two general hospitalsen_US
dc.typeArticleen_US
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