Favorable attributes and biological effects of Palestinian Botanical Extracts of Punica Granatum

Enas Shqair Ahmad Shqair
ايناس شقير أحمد شقير
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Al-Quds University
Pomegranate (Punica granatum L.) is an ancient tree in Palestine and the Arabic world that has many benefits in food, cosmetics, health, and medicine to treat some prevalent diseases like diabetes. Non-enzymatic glycation generates a diverse set of compounds known as advanced glycation endproducts (AGEs) that accumulate in the body and cause the development of chronic diseases in humans, such as type-2 diabetes, atherosclerosis, and alzahemir. Therefore, the development of a natural AGEs inhibitor needs extensive research investigation. Pomegranate peel extracts (PPEs) with rich antioxidants such as tannin and phenols show considerable ability as natural inhibitors in treating diabetics. In the present study, the hydrozable tannins (HTs) of pomegranate peel (PP) were extracted by sonication (Extract A) and reflux (Extract B) methods with the same solvents. For the comparison with hydrozable tannins, ethanol (Extract E) and acetone (Extract F) solvents were used to extract tannins and other chemicals as a mixture. The anti-glycation production of end products was assessed with four types of extracts by using an in vitro glucose-bovine serum albumin (BSA) test. The antioxidant effects were evaluated by two methods: 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging and the ferric reducing antioxidant power assay (FRAP). A Folin- 2 Ciocalteau test was used to determine total phenolic content (TPC), and a colorimetric assay was used to determine total flavonoid content (TFC). The antibacterial effects were evaluated by the disc-diffusion method to investigate the inhibition zone of each extract versus gram positive bacteria (MRSA and S.aureus) and gram negative bacteria (E. coli and pseudomonas). The obtained
Shqair، Enas Shqair. (2022). Favorable attributes and biological effects of Palestinian Botanical Extracts of Punica Granatum [رسالة ماجستير منشورة، جامعة القدس، فلسطين]. المستودع الرقمي لجامعة القدس. https://arab-scholars.com/8d66ec