Radiation induced delayed transverse myelitis and neurological deficit at tertiary care center

dc.contributor.author Abuzneid, Yousef S.
dc.contributor.author Al-Janazreh, Hamdi
dc.contributor.author Haif, Motasem
dc.contributor.author Idais, Shahd T.
dc.contributor.author Asakrah, Baraa
dc.contributor.author Ajwa, Sufana M.
dc.contributor.author Sarahneh, Shifa
dc.contributor.author Abdeen, Hani
dc.date.accessioned 2021-12-18T12:25:13Z
dc.date.available 2021-12-18T12:25:13Z
dc.date.issued 2021-09-20
dc.description.abstract Background: Transverse myelitis is a rare spinal cord inflammation with absence of a compression. It varies in presentation based on the pathology location, and mainly causes a combined deficit of motor, sensory, and autonomic functions. History, physical examination, and other diagnostic tests including blood tests and an MRI are important tools to establish a diagnosis. A thorough neurological evaluation helps localize the affected region of the spinal cord. The management in- cludes rehabilitation as any other spinal cord injury. If very severe, a multidisciplinary rehabilitation program will be required. Presentation: We explain a case in which a 43-year-old male patient, known to have chronic myelogenous leu- kemia (CML), on Imatinib (a tyrosine kinase inhibitor), started complaining of back pain at the level of the 10th rib. Different tests were made including a PET-CT (Positron Emission Tomography-Computed Tomography) which showed hypermetabolic bony lytic lesion in the left mandible at the level of temporomandibular joint, destruction of the 10th rib, and no evidence of spinal cord compression. Other etiologies were excluded, making transverse myelitis due to radiation for the patient’s CML on top of the differential diagnosis. Conclusion: A thorough physical examination and diagnostic tests are important tools to exclude other etiologies of complex neurological deficit in a patient with CML. en_US
dc.identifier.uri https://dspace.alquds.edu/handle/20.500.12213/6503
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.subject CML en_US
dc.subject TBI en_US
dc.subject Transverse myelitis en_US
dc.subject Rare en_US
dc.subject Case report en_US
dc.title Radiation induced delayed transverse myelitis and neurological deficit at tertiary care center en_US
dc.type Article en_US
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