Cerebellar liponeurocytoma, a rare tumor: Case report and review of the literature
Date
2021-04-30
Authors
Abuzneid, Yousef
Alzeerelhouseini, Hussam
Shkokani, Sundus
Aqel, Wafa
Aldarawish, Asad
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Introduction: Cerebellar liponeurocytoma is a rare tumor of the central nervous system occurring mainly in the
posterior fossa, which shows neuronal and variable astrocytic differentiation, along with foci of lipomatous
differentiation.
Case presentation: Herein, we describe a 50-year-old female patient who presented to the hospital complaining of
headache, tinnitus, and vertigo with positive cerebellar signs. MRI revealed a left cerebellar tumor. After tumor
resection, histological examination and immunohistochemistry were done and the diagnosis of cerebellar liponeurocytoma
was confirmed.
Discussion: Liponeurocytoma may be mistaken as a medulloblastoma with lipidized cells or a lipomatous ependymoma.
Histopathological examination, reinforced by immunohistochemistry and electron microscopy, are
required to distinguish between these entities. The rarity of this tumor and paucity of pertinent information
regarding its biological potential and natural history have resulted in the application of various treatment
modalities.
Conclusion: Liponeurocytoma is a rare benign tumor with cerebellum is the typical site for it. Although surgery is
the treatment of choice; however, postoperative radiotherapy may have a role in case of incomplete tumor
resection or recurrence.