Systolic inter-arm blood pressure difference and estimated glomerular filtration rate in type 2 diabetic patients in Palestine: a cross-sectional study

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dc.contributor.authorRaghad sweity
dc.contributor.authorKhadeeja Fanoun
dc.contributor.authorTareq Jarrar
dc.contributor.authorBayan F. alqtishat
dc.contributor.authorMohammad abdelhafez
dc.contributor.authorSuheir Ereqat
dc.date.accessioned2024-06-24T06:16:02Z
dc.date.available2024-06-24T06:16:02Z
dc.date.issued2023-09-25
dc.description.abstractObjectives: this study aimed to investigate the association between systolic inter-arm blood pressure difference (iaBPD) and the estimated glomerular filtration rate (eGFR), as well as chronic kidney disease (cKD), in patients with type 2 diabetes mellitus (t2DM).Patients and methods: this cross-sectional study included 189 Palestinians diagnosed with t2DM. Data were collected through personal interviews, medical records and three separate blood pressure measurements from both arms. Patients were stratified in two ways: based on systolic iaBPD ≥15 mmhg and the presence of cKD, indicated by an eGFR of <60 ml/min/1.73 m2 over a three months period. We used simple and multiple linear regression analyses to clarify the association between systolic iaBPD (mmhg) and eGFR and to identify independent predictors for eGFR.Results: the mean age was 61.3 years, with a female percentage of 57.7%. the prevalence of systolic iaBPD ≥15 mmhg and cKD was 27.5% and 30.2%, respectively. among patients with eGFR <60 ml/min/1.73 m2, the median systolic iaBPD was 12.5 mmhg (interquartile range (iQR), 13.5 mmhg), whereas in patients with eGFR ≥60 ml/min/1.73 m2, it was 7.5 mmhg (iQR, 9.8 mmhg) with a significant difference (p = .021). the results of the multiple linear regression model did not reveal an independent association between systolic iaBPD and eGFR, with an unstandardized coefficient (B) of −0.257 (95% confidence interval (ci), −0.623 to 0.109; p = .167). however, older age (B, −0.886; 95% ci, −1.281 to −0.49; p < .001), hypertension (B, −12.715; 95% ci, −22.553 to −2.878; p = .012) and a longer duration of DM (B, −0.642; 95% ci, −1.10 to −0.174; p = .007) were significantly and negatively associated with eGFR.Conclusions: systolic iaBPD did not exhibit an independent association with eGFR in t2DM patients. however, older age, a previous history of hypertension, and a longer duration of DM were all significantly associated with lower eGFR.
dc.description.sponsorshipThe authors thank each of Baraah Farun, Peter Bael, aya siaj, aseel Nassar, alhareth amro, Yahya abu Jwaid, Bayan awad, adan Rabayah, Basel Zaben, Natalie Khamashta, Mo’men alashwas, anas Barabrah, anas toqan, Mohammad shehadeh and Raya amer for their assistance in the data collection for this project.
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/9268
dc.language.isoen
dc.publisherTaylor and Francis
dc.titleSystolic inter-arm blood pressure difference and estimated glomerular filtration rate in type 2 diabetic patients in Palestine: a cross-sectional study
dc.typeArticle
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