Non-Covalent Functionalization of Graphene Sheets with Surfactants and their Antibacterial Activity
Date
2016-12-01
Authors
Assali, Mohyeddin
Mousa, Ameera
Thiab, Saja
Al-ott, Maha
Abu Taha, Adham
Faroun, Maryam
Gomez, Pablo Romero
Journal Title
Journal ISSN
Volume Title
Publisher
Deanship of Scientific Research at An Najah National University (ANNU)
Abstract
Graphene is a monolayer of tightly packed carbon atoms that attracted tremendous research
interest in recent years, owing to its interesting physical, chemical, electrical, mechanical and
optical properties and has numerous exciting applications. However, it suffers from low water
solubility which limits its biological application. Therefore, the aim of this work is to functionalize
the graphene sheets non covalently with various charged surfactants (cationic- Cetrimide,
nonanionic-Tween 80, anionic-Sodium dodecyl sulfate) to get a highly stable conjugate soluble in
water and to improve the antibacterial activity of this nano-derivative. The morphology and the size
of the functionalized graphene were determined by atomic force microscopy. Moreover, the
functionalized graphene was quantified by thermogravimetric analysis obtaining the maximum
functionalization in the case of citrimide functionalized graphene. The antibacterial activity against
Staphylococcus aureus and Pseudomonas aeruginosa has been studied. The results indicate that
only the functionalized graphene with citrimide has significant antibacterial activity against the two
strains of bacteria S. aureus and P. aeruginosa with MIC 0.98, 7.81 mg/L respectively.
Description
Keywords
Graphene , Surfactants , Antibacterial Activity