Incidence of Septicemia among Infants at El-Nassr Hospital Gaza Governorate - 2007

Ameed Awny Mushtaha
عميد عوني فوزي مشتهى
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Al-Quds University
A descriptive and analytical cross sectional study was performed in Gaza Governorate from 1 October (2006) to 30 September (2007). The aim of this study was to identify the incidence, the distribution and the risk factors of septicemia disease among infants less than 1 year admitted to El-Nassr pediatric hospital, and to assess the association between certain laboratory results and the severity and prognosis of the disease. Data was collected through a structural questionnaire administered to 366 subjects parents. Response rate was 100%. The incidence rate of septicemia disease in El-Nassr pediatric hospital was 58/1000 infant. Clear variations were found in the incidence according to sex, age groups, governorates, socio-demographic, economic status, microorganisms causing septicemia and antibiotic resistance. The disease was prominent among neonates with age less than 28 day with percentage 49.5%. The risk age group was children less than 8 days with fatality rate 20%. The total fatality rate was 10.1%, and it was higher among females. Low socio-economic status, families of high crowding index, parents of low educational level and with low income jobs were associated with the disease, and its severity. There was clear seasonal variation in incidence of disease with a peak in winter and summer. Gram positive bacteria was more prominent in our study pateints with percent of 79%, while Gram-negative bacteria was less prominent in percent of 21%. However the fatality rate in Gram-negative bacteria was 23.4% compare with 6.6% in Gram-positive bacteria. Results show that high percentage of bacteria was resistant to cloxacillin (77.8%) while it was lower with Meropenem (25%). On other hand the study demonstrates that bacteria were sensitive to Ciprofloxacin (100%), Penicilline (90%) and Amikacin (86.2%). Our study contributes in highlighting the major risk factors for implementing strategies that could help in prevention of Septicemia disease. Therefore, we recommend the need for application of vaccination programs against some types of bacteria that cause Septicemia iv as H. influenzae type b, S. pneumoniae and N. meningitides serogroup W135 especially for infants. Furthermore, high index of suspicion is needed among the medical staff for early diagnosis and treatment of septicemia.