SEX-SPECIFIC ASSOCIATION OF THE MAOA RS1137070 POLYMORPHISM WITH INTERNET ADDICTION SEVERITY AMONG AL-QUDS UNIVERSITY STUDENTS-PALESTINE: A CROSS-SECTIONAL STUDY
Date
2026-05-12
Authors
Toqa Jawabreh
Abed Al-Majeed Nasereddin
Journal Title
Journal ISSN
Volume Title
Publisher
Deanship of Scientific Research - Al-Quds University
Abstract
The rapid expansion of Internet usage has raised concerns about a possible association between Internet Addiction (IA) and a person's genetic predisposition. Studies indicate that the functional variation in the gene that encodes the enzyme monoamine oxidase A (MAOA) may affect the regulation of neurotransmitters involved with reward processing and impulse control, both of which relate to excessive Internet use. However, the role that MAOA polymorphisms play in the development of IA has not been well characterised; especially when it comes to identifying sex-specific differences regarding their effects. Objective: The goal of this study was to determine the associations between MAOA rs1137070 polymorphisms and IA severity, while considering demographic and academic characteristics and possible differences in the effect of the MAOA polymorphisms between males and females.