Phenolic and Flavonoids Analysis of Pomegranate Peel Extracts and their Antiniflammatory and Antioxidant Activities

dc.contributor.author K, Qabaha
dc.contributor.author F, Al-Rimawi
dc.contributor.author S, Nusseibeh
dc.contributor.author J, Abbadi
dc.contributor.author S, Abu-Lafi
dc.date.accessioned 2019-11-30T12:03:11Z
dc.date.available 2019-11-30T12:03:11Z
dc.date.issued 2019-03-25
dc.description.abstract An in-vitro evaluation of the anti-inflammatory and antioxidant activities of pomegranate peel extract from Palestine were investigated. In parallel, the total phenolic content (TPC) and the total flavonoids content (TFC) were measured. The antioxidant activities were determined spectrophotometrically by DPPH, FRAP, CUPRAC and the ABTS methods. The phenolic and flavonoid contents were separated and partially identified using HPLC and LC-MS. In-vitro inhibitory effect of the extract on production of Interlukin-6 (Il-6) and Tumor Necrosis Factor-α (TNF-α) by Lipopolysacaride (LPS)-induced polymorphonuclear Cells (PMNCs) was evaluated. Pomegranate peel extract was found to have strong antiinflamatory activity as revealed by the reduction in the levels of IL-6 and TNF-alfa. It was also found that it is rich in phenoloic and flavonoids that enhanced its reducing activity and free radical scavenging ability. en_US
dc.identifier.citation International Journal of Pharmaceutical Quality Assurance en_US
dc.identifier.issn 0975 9506
dc.identifier.uri https://dspace.alquds.edu/handle/20.500.12213/4974
dc.language.iso en en_US
dc.subject Pomegranate peel en_US
dc.subject extract en_US
dc.subject anti-inflammatory en_US
dc.subject antioxidant activity en_US
dc.subject Phenolic compounds en_US
dc.subject flavonoids en_US
dc.title Phenolic and Flavonoids Analysis of Pomegranate Peel Extracts and their Antiniflammatory and Antioxidant Activities en_US
dc.type Book en_US
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