Pharmacovigilance and Adverse Drug Reactions Reporting Process in West-Bank, Palestine
Date
2016-10-09
Authors
Khdour, Maher
Yaghmour, Nima
Hallak, Hussein
Dweib, Mohammad
Al-Shahed, Qusai
Jarab, Anan
Journal Title
Journal ISSN
Volume Title
Publisher
Deanship of Scientific Research at An Najah National University
Abstract
Active national pharmacovigilance programmes are needed to monitor adverse drug reaction (ADR)
data in local populations. The objective of this study was to describe the knowledge, experiences, attitudes
and perceived barriers to reporting of suspected ADRs by community and hospital pharmacists in
West Bank, Palestine. Between December 2014 and March 2015 we conducted a survey about the
knowledge and attitude of pharmacists (n = 270) using a face-to-face questionnaire. The questionnaire
consisted of questions about the sociodemographic characteristics of the pharmacists, their knowledge of
pharmacovigilance and their attitudes towards ADR reporting. Main outcomes measured: The majority of
the pharmacists (62.6%) worked in the community pharmacies and more females responded to the questionnaire
than males (59% vs 41%). only 11.9% could conceptually or actually define
‘pharmacovigilance’ correctly while one quarter of the respondent pharmacist (24.9%) could define ADR
correctly. The hospital clinical pharmacists defined ‘pharmacovigilance’ correctly with higher significance
(P<0.001) when compared with community pharmacists. Only 12.2% had ever reported an ADR.
The majority of these reports (85%) done by the hospital pharmacists (p<0.0001). The main reasons that
discourage the pharmacists from reporting ADRs were ‘‘no enough information available from the patient
(76.7%)’’, and ‘‘they did not know how to report (66.7%)’’. The majority of the respondents (92.0%) felt
that reporting ADR was their duty and (82%) participants were interested in participating in the National
Pharmacovigilance Programme in Palestine. The results show that Palestinian pharmacists have poor
knowledge about pharmacovigilance. There is an urgent need for educational programs to train them
about pharmacovigilance and ADR reporting scheme.
Description
Keywords
Pharmacovigilance , Adverse Drug Reaction , Reporting , Palestine