Assessment of the inhalation technique and adherence to therapy and their effect on disease control in outpatients with asthma

dc.contributor.authorKhdour, Maher R.
dc.contributor.authorElyan, Sabrin O.
dc.contributor.authorHallak, Hussein O.
dc.contributor.authorJarab, Anan S.
dc.contributor.authorMukattash, Tareq L.
dc.contributor.authorAstal, Amr
dc.date.accessioned2019-11-17T17:49:06Z
dc.date.available2019-11-17T17:49:06Z
dc.date.issued2019-02-21
dc.description.abstractObjectives The objective of this study was to assess correct use of inhaler devices, adherence to inhaler corticosteroid treatment and their effects on asthma control. Methods This study was a prospective, single-centre, observational study conducted between July and February 2016 at Al-Makased Hospital, respiratory outpatient clinic. Inhaler technique of asthma patients using pressurized metered-dose inhalers or dry powder inhalers (Turbuhaler (TH) and Accuhaler DiskusTM (ACC)) were assessed against published inhaler technique checklists. Asthma control variables measured using Asthma Control Test (maximum 25, higher score corresponding to better asthma control) were assessed, and adherence to asthma medications was assessed by Morisky adherence scale. Key findings Two hundred and twenty patients were recruited in the study. The mean age was 42.3 15.2 years and 59.1% were male. One hundred and seventeen (53.2%) were using TH, 60 (27.3%) were using ACC and 43(19.5%) were using MDIs. Only 22 (10%) were smoker and only 48 (21.8%) patients were their asthma controlled (ACT score >20). The devices were used correctly by 79.1% of patients using MDI, 69% of ACC and 55.6% of TH users (P > 0.001). The most common improper step was ‘forceful inhalation’ (65.4%) made by the MDI users, ‘Not exhaling to residual volume’ (58.7%) made by ACC users and ‘Not inhaling deeply enough’ (52.2%) made by TH users. Multivariate analysis showed that the likelihood of having controlled asthma was significantly higher in those with correct inhaler techniques (OR 2.3; 95% CI: 1.08–4.77; P = 0.028), high adherence to medications (OR 2.37; 95% CI: 1.05–4.92; P = 0.03) and having a higher level of education (OR 2.58; 95% CI: 1.19–3.63; P = 0.018). Conclusions It was found that asthma control was better among correct users. Repetitive training about using devices may contribute improving inhaler technique.en_US
dc.description.sponsorshipThis research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.en_US
dc.identifier.citationTY - JOUR AU - Khdour, Maher AU - Elyan, Sabrin AU - Hallak, Hussein AU - Jarab, Anan AU - Mukattash, Tareq AU - Astal, Amr PY - 2019/02/01 SP - T1 - Assessment of the inhalation technique and adherence to therapy and their effect on disease control in outpatients with asthma DO - 10.1111/jphs.12290 JO - Journal of Pharmaceutical Health Services Research ER -en_US
dc.identifier.issn1759-8885
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/4927
dc.language.isoenen_US
dc.publisherWileyen_US
dc.subjectadherenceen_US
dc.subjectAsthma Control Testen_US
dc.subjectcounsellingen_US
dc.subjectinhaler techniqueen_US
dc.subjectPalestineen_US
dc.subjectpatient educationen_US
dc.titleAssessment of the inhalation technique and adherence to therapy and their effect on disease control in outpatients with asthmaen_US
dc.typeArticleen_US
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