A pyoderma gangrenous‑like cutaneous leishmaniasis in a Libyan woman with rheumatoid arthritis: a case report

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dc.contributor.authorAl‑Dwibe, Hamida
dc.contributor.authorAmro, Ahmad
dc.contributor.authorGashout, Aisha
dc.contributor.authorEl‑Zurghany, Ali
dc.contributor.authorEl‑zubi, Said
dc.contributor.authorEl‑Hashme, Mohamed
dc.contributor.authorHamarsheh, Omar
dc.contributor.authorMaree, Mokhtar
dc.date.accessioned2020-01-29T19:50:47Z
dc.date.available2020-01-29T19:50:47Z
dc.date.issued2018-03-01
dc.description.abstractBackground: Several case reports describe diseases presenting with skin ulcerations, which resemble pyoderma gangrenosum especially in immune-compromised patients, often proven on further workup, to have an infective or malignant etiology. However, treatment of pyoderma gangrenosum by systemic steroids or other immunosuppressive agents may worsen the condition. Case presentation: We report here, a 45 year-old Libyan woman with rheumatoid arthritis on low dose steroids with pyoderma gangrenosum-like skin lesions and positive pathergy. Slit–smear was positive for Leishmania amastigotes and histopathological examination confirmed the diagnosis of cutaneous leishmaniasis. The lesions healed completely by parenteral sodium stibogluconate (Pentostam) 600 mg daily. Conclusion: We report for the first time, a rare and unusual presentation of pyoderma gangrenosum like-cutaneous leishmaniasis in a patient with rheumatoid arthritis. Atypical cutaneous leishmaniasis should not be ruled out in the differential diagnosis of unresponsive skin diseases, with slit/smear and a skin biopsy is required.en_US
dc.description.sponsorshipAcknowledgements Not applicable. Funding The authors declare that no funding support was obtained for this study.en_US
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/5060
dc.language.isoenen_US
dc.publisherBMCen_US
dc.subjectLeishmaniaen_US
dc.subjectPyoderma gangrenousen_US
dc.subjectCutaneous leishmaniasisen_US
dc.subjectRheumatoid arthritisen_US
dc.titleA pyoderma gangrenous‑like cutaneous leishmaniasis in a Libyan woman with rheumatoid arthritis: a case reporten_US
dc.typeArticleen_US
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