dc.contributor.author | Khdour, Maher R. | |
dc.contributor.author | Agus, Ashley M. | |
dc.contributor.author | Kidney, Joseph C. | |
dc.contributor.author | Smyth, Bronagh M. | |
dc.contributor.author | Elnay, James C. | |
dc.contributor.author | Crealey, Grainne E. | |
dc.date.accessioned | 2018-09-18T11:59:06Z | |
dc.date.available | 2018-09-18T11:59:06Z | |
dc.date.issued | 2011-06-04 | |
dc.identifier.issn | 2210-7711 | |
dc.identifier.uri | https://dspace.alquds.edu/handle/20.500.12213/949 | |
dc.description.abstract | Objective: To undertake a cost-utility analysis
(CUA) of a pharmacy-led self-management programme for
Chronic Obstructive Pulmonary Disease (COPD). Setting:
A single outpatient COPD clinic at the Mater Hospital,
Belfast, Northern Ireland between. Method: CUA alongside
a randomised control trial. The economic analysis used
data from 127 COPD patients aged over 45 years, with an
FEV1 of 30–80% of the predicted normal value. Participants
received either a pharmacy-led education and selfmanagement
programme, or usual care. One year costs
were estimated from the perspective of the National Health
Service and Personal Social Services and quality-adjusted
life years (QALYs) were calculated based on responses to
the EQ-5D at baseline, 6 and 12 months. Main outcome
measure: Cost per QALY gained. Results: The mean differences
in costs and effects between the self-management
and education programme and usual care were -£671.59
(95 CI%: -£1,584.73 to -£68.14) and 0.065 (95% CI;
0.000–0.128). Thus the intervention was the dominant
strategy as it was both less costly and more effective than
usual care. The probability of the intervention being costeffective
was 95% at a threshold of £20,000/QALY gained. Sensitivity analyses indicated that conclusions were robust
to variations in most of the key parameters. Conclusion:
The self-management and education programme was found
to be highly cost-effective compared to usual care. Further
research is required to establish what aspects of self-management
and education programmes have the greatest
impact on cost-effectiveness. | en_US |
dc.description.sponsorship | Acknowledgments We are very grateful for the advice and feedback
provided by the anonymous reviewers of this paper during its
revision.
Funding The authors wish to thank Chest Heart and Stroke
(Northern Ireland) for financial support. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Springer Science+Business Media B.V. 2011 | en_US |
dc.subject | COPD | en_US |
dc.subject | Cost-effectiveness analysis | en_US |
dc.subject | Costutility analysis | en_US |
dc.subject | Education | en_US |
dc.subject | RCT | en_US |
dc.subject | Self-management | en_US |
dc.subject | United Kingdom | en_US |
dc.title | Cost-utility analysis of a pharmacy-led self-management programme for patients with COPD | en_US |
dc.type | Article | en_US |