Reinforcement Learning Predicts Response to SSRIs in Medication-Naïve Patients with Major Depressive Disorder

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dc.contributor.authorYasmeen Sultan
dc.contributor.authorMahmud A. Sehwail
dc.contributor.authorMohammad M. Herzallah
dc.date.accessioned2022-06-22T11:49:53Z
dc.date.available2022-06-22T11:49:53Z
dc.date.issued2022-05-11
dc.description.abstractBackground: Patients with major depressive disorder (MDD) exhibit hyposensitivity to positive reinforcement and hypersensitivity to negative reinforcement. In patients who respond to treatment, selective serotonin reuptake inhibitor (SSRI) antidepressants arguably modulate MDD symptoms by attenuating learning from negative reinforcement. However, only 30% of patients with MDD respond to antidepressants including SSRI. Cognitive differences between responders and non-responders were heretofore not investigated medication-naïve patients with MDD.
dc.identifier.urihttps://hdl.handle.net/20.500.12213/6593
dc.language.isoen
dc.publisherAl-Quds University, Deanship of Scientific Research
dc.titleReinforcement Learning Predicts Response to SSRIs in Medication-Naïve Patients with Major Depressive Disorder
dc.typeArticle
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