Types and Trends Of Pediatric Cancer in Gaza Governorates During The Period 1998 -2010

Reem Mahmoud Al Zeer
ريم محمود الزير
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Al-Quds University
Background: Cancer is a serious disease and has special and global concern. It is considered one of the largest burdens in the global burden of disease. There is a steep increase in incidence of cancer everywhere. Aim: Assessing the types and trend of pediatric cancer in Gaza strip during the period 1998 to 2010 Methodology: The design of this study is descriptive, comparative and record based study for the cancer data. The data was collected from Gaza cancer registry and other cancer health services sites. We applied special designed abstract sheet to measure the current frequency and characteristics of the event in the population. Results: The total of 904 cases of childhood cancer was reported in Gaza strip during the period from 1998 to 2010. The annual average of cases was about 70 pediatric cancer cases per year. Average annual percentage change is (+4.4%). Males are exposed more than females, where 502 cases of the event for males (55.7%) with ASR 110 and 402 for females (44.3%) with ASR 90. Male/female ratio is 1.25:1. The study results showed that the highest event incidence was among age group (0-4) 39.5%, followed by age group (5-9) 33%, (10-15) 27.9%. The Gaza city has the majority of cases (49.7%). The types of cancer showed, one-third of all childhood cancers were leukemia 255 cases (27.9%), lymphomas 17.6%, while brain and spinal tumor representing 15.8%. The incidence was highest in the 0–4 age group 356 cases (ASR 101), followed by 5–9 with 296 case (ASR 104), and 10–15 age group 253case (ASR 90). Leukemia and neuroblastoma and tumors of connective tissue were predominantly among 0–4 age group. H.D and bone tumor incidence in 10–15, in N.H.D. the highest incidence was seen in 5-9 age groups. There was male predominant in lymphomas and leukemia. Over this period the total mortality counted for 336 reported deaths among pediatrics cancer with an annual average 25 deaths per year. The proportional death rate due to cancer among children was 3.12% from total child deaths. Conclusion: There were no consistent large changes in incidence for the major types of cancer among children aged 0-15 years during 1998 to 2010. The modest increases for childhood were CNS cancers and leukemia. This pattern suggests that the increases likely reflected reporting or diagnostic changes rather than effects of environmental influences. Cancer is still considering a rare disease among children, on average one child can develop cancer per 10.000 each year in Gaza governorates. We recommend further investigation and more deep analysis for pediatric cancer and we think that the policy makers should have developing a strategic plan for monitoring and control the incidence of cancer in Palestine