THE ROLE OF CIRCULATING MICROBIAL DNA (CF-MBDNA) AS AN EARLY BIOMARKER OF CHRONIC INFLAMMATION IN LONG-STANDING DIABETES MELLITUS AND ITS ASSOCIATION WITH MICROVASCULAR COMPLICATIONS: A SYSTEMATIC REVIEW

Simple item page
dc.contributor.authorAbdullah Talal Salem
dc.contributor.authorFaisal Aljohani
dc.contributor.authorNuha Al Yousfi
dc.contributor.authorBashayr Alkuhayli
dc.contributor.authorAhmed Isa
dc.contributor.authorArwa Hammouda
dc.contributor.authorYara Alamri
dc.contributor.authorAbdullah Almohamad Almustafa
dc.contributor.authorAlaa Habashi
dc.contributor.authorSiraj Fakiha
dc.contributor.authorRahaf Alqahtani
dc.contributor.authorMohammed Alsaeed
dc.date.accessioned2026-09-14T08:06:57Z
dc.date.available2026-09-14T08:06:57Z
dc.date.issued2026-05-12
dc.description.abstractBackground: Circulating microbial DNA (cf-mbDNA) and related cell-free DNA (cfDNA) fragments have emerged as novel biomarkers reflecting metabolic stress, inflammation, and vascular injury in diabetes mellitus (DM). This systematic review aimed to synthesize current evidence on their diagnostic potential for detecting chronic inflammation and microvascular complications in long-standing diabetes. Study Purpose/ Objectives: The role of circulating microbial DNA (cf-mbDNA) as an early biomarker of chronic inflammation in long-standing diabetes mellitus and its association with microvascular complications: A systematic review Methods: Following PRISMA 2020 guidelines, ten peer-reviewed studies published between 2010 and 2025 were systematically analyzed across multiple databases. Eligible studies assessed cfDNA or cf-mbDNA in plasma or serum samples from patients with type 1 or type 2 diabetes, investigating associations with inflammatory and vascular markers.
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/10778
dc.language.isoen
dc.publisherDeanship of Scientific Research - Al-Quds University
dc.titleTHE ROLE OF CIRCULATING MICROBIAL DNA (CF-MBDNA) AS AN EARLY BIOMARKER OF CHRONIC INFLAMMATION IN LONG-STANDING DIABETES MELLITUS AND ITS ASSOCIATION WITH MICROVASCULAR COMPLICATIONS: A SYSTEMATIC REVIEW
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
THE ROLE OF CIRCULATING MICROBIAL DNA (CF-MBDNA) AS AN EARLY BIOMARKER OF CHRONIC INFLAMMATION IN LONG-STANDING DIABETES.pdf
Size:
287.08 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.61 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Medicine