Now showing items 1-6 of 6
Mefenamic acid Prodrugs and Codrugs- Two Decades of Development
prodrugs are bioreversible derivatives of drug molecules that undergo intermolecular or intramolecular reactions by enzymatic or chemical biotransformation in the human body to give the corresponding active parent drugs ...
Prodrugs targeting the central nervous system (cns)
The classical approach for delivery of drugs into the central nervous system (CNS) is associated with adverse effects and it has many limitations. Therefore, extensive efforts have been done in searching and developing ...
Anti-cancer Prodrugs-Three Decades of Design
The conventional old treatment method for cancer therapy is associated with severe side effects along with several limitations. Therefore, searching and developing new methods for cancer became crucial. This mini review ...
Antibacterial Predrugs-from 1899 till 2015
(WJPPS,Dr. T Pal, 2015-07-08)
The predrug (prodrug) term involves chemically modified inert compound which upon an administration releases the active parent drug to elicit its pharmacological response within the body. For many years, the predrug ...
A Novel Mathematical Equation For Calculating The Number of ATP Molecules Generated From Sugars In Cells
(WJPR,Tara Pal,WJPR, 2015-05-23)
Adenosine triphosphate (ATP) is critical for all life from the simplest to the most complex. All organisms from the microscopic to humans utilize ATP as the source for their primary energy currency. This manuscript ...
Diclofenac Codrugs and Prodrugs-Three Decades of Design
(WJPPS,Dr. T Pal, 2015-06-08)
Prodrugs or predrugs are inactive molecules which become active after in vivo conversion to release the active parent drug. The prodrug’s cleavage can be catalyzed by metabolic enzymes or can occur by chemical means without ...