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Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
Alzheimer’s disease (AD) is a disorder that causes degeneration of the cells in the brain and it is the main cause of dementia, which is characterized by a decline in thinking and independence in personal daily activities. ...
Resistance of Gram-Positive Bacteria to Current Antibacterial Agents and Overcoming Approaches
The discovery of antibiotics has created a turning point in medical interventions to pathogenic infections, but unfortunately, each discovery was consistently followed by the emergence of resistance. The rise of ...
Enzyme Models—From Catalysis to Prodrugs
Enzymes are highly specific biological catalysts that accelerate the rate of chemical reac-tions within the cell. Our knowledge of how enzymes work remains incomplete. Computationalmethodologies such as molecular mechanics ...
Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It
Antimicrobial resistance represents an enormous global health crisis and one of the most serious threats humans face today. Some bacterial strains have acquired resistance to nearly all antibiotics. Therefore, new ...
Antibacterial Prodrugs to Overcome Bacterial Resistance
Bacterial resistance to present antibiotics is emerging at a high pace that makes the development of new treatments a must. At the same time, the development of novel antibiotics for resistant bacteria is a slow-paced ...