Pyrazine derivatives possess numerous pharmacological effects including but not limited to antiviral, antibiotic, antifungal, diuretic, anticonvulsant, antidiabetic, analgesic and anti proliferative effect. Consequently, ...

Parkinson patients have insufficient dopamine in specific regions of the brain, so attempts have been made to replenish the deficiency in the dopamine. Dopamine itself doesn't cross blood brain barrier, but its precursor, ...

Background and objectives: Unraveling the mechanisms of a number of enzyme models has allowed for the design of efficient chemical devices having the potential to be utilized as prodrug linkers that can be covalently ...

Pregabalin is an anticonvulsant agent used for the peripheral and central neuropathic pain treatment, marketed as Capsule and Solution dosage forms. The purpose of this study is to develop an immediate release Pregabalin ...

Quantitative structure-activity relationship study was performed to understand the activity of a set of 136 ligands of Translocator protein (TSPO) compounds. QSAR models were developed using multiple linear regression ...

The two novel prodrugs of amoxicillin and cephalexin were synthesized to improve the stability and bitter taste of their parent drugs. The in vitro susceptibility for both prodrugs was determined against Escherichia coli, ...

This study was aimed to identify the reality of the activities of the National Committee for Palestinian Summer Camps, In terms of making children acquire life skills for the year 2011-2012. These skills are (contact and ...