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تصميم و تحضير مشتقات البيريميدين ثلاثية التفرع كمثبطات لبروتين مرافق المنشط لمستقبلات الاستروجينDesign and Synthesis of Trisubstituted Pyrimidine Derivatives as Coactivator Binding Inhibitors (CBIs) of Estrogen Receptor Signaling
(AL-Quds Universityجامعة القدس, 2016-01-09)
Breast cancer (BC) is one of the most commonly diagnosed cancers in women. Estrogen signaling
and the estrogen receptors (ERα, ERβ) are implicated in breast cancer progression. Majority of
breast cancers start out as ...
تأثيرمركبات لتيولين، ميدستيورين (PKC-412) و PD173074 على مراحل حياة فيروس Cytomegalovirus (HCMV) المختلفة.The role of Luteolin, Midostaurin( PKC-412) and PD173074 in Human Cytomegalovirus (HCMV) life cycle
(AL-Quds Universityجامعة القدس, 2016-04-25)
The cytoplasmic assembly compartment (AC) in HCMV-infected human foreskin
fibroblasts (HFF) is a unique juxtanuclear ―bulb‖-like structure. Morphology of the AC is
dependent on the activity of the viral-encoded ...
تطوير وتقييم شكل صيدلاني جديد بخاصية التحرر الفوري (أقراص بريغابالين)Formulation and Evaluation of Immediate Release Pregabalin Tablets
(AL-Quds Universityجامعة القدس, 2016-05-21)
Pregabalin is an anticonvulsant agent used for the peripheral and central neuropathic pain
treatment, marketed as Capsule and Solution dosage forms. The purpose of this study is to
develop an immediate release Pregabalin ...
تصنيع ودراسة المواصفات والقوى المحركة المخبرية للأدوية المساعدة للدوبامينSynthesis, Characterization and in Vitro Kinetic Study of Dopamine Prodrugs
(AL-Quds Universityجامعة القدس, 2016-12-21)
Parkinson patients have insufficient dopamine in specific regions of the brain, so attempts have
been made to replenish the deficiency in the dopamine. Dopamine itself doesn't cross blood brain
barrier, but its precursor, ...
التركيب الكيميائي والخصائص والقوى المحركة المخبرية لدوائيْن أوليّيْن جديديْن مبتكريْن من مضادات البكتيريا؛ الأموكسيلين والسيفالكسينSynthesis, Characterization and In Vitro Kinetics of Amoxicillin and Cephalexin Antibacterial Prodrugs
(AL-Quds Universityجامعة القدس, 2014-02-22)
Marketed antibacterial drugs suffer several problems, such as bitter taste and low stability
which lead to patient incompliance. Prodrug technology for solving such problems is
extremely exciting. Based on previously ...
تطوير دواء اولي مبتكر للاتوفاكوون? الدواء المضاد للملاريا: تصنيع كيميائي, تشخيص و تقييم القوى المحركه المخبريهNovel Anti-malarial Atovaquone P rodrug: Synthesis,Characterization and in vitro Kinetics Study
(AL-Quds Universityجامعة القدس, 2016-01-05)
Malaria is a global public health problem, resulting in tow million deaths per year .The
majority of death cases are due to the most severe form of malaria caused by Plasmodium
falciparum. As a result, efforts were ...
تصنيع ودراسة لمواصفات الأدوية المساعدة المصممة لمادة الغايفينيسينSynthesis and Characterization of Designed Guaifenesin Prodrugs
(AL-Quds Universityجامعة القدس, 2014-02-25)
Guaifenesin is an extremely bitter taste substance which affects its usage in pediatric and
geriatric formulations. In this thesis we aimed to mask the bitter taste of guaifenesin by
converting it to a potential tasteless ...
تصنيع ودراسة المواصفات ل الأدوية المساعده المصممة ل حمض ترانزاميك و براسيتامولSynthesis and Characterization of Designed Tranexamic Acid and Paracetamol Prodrugs
(AL-Quds Universityجامعة القدس, 2014-02-22)
Prodrug is a chemical devise in which the drug is covalently linked to a chemical moiety; this
linked moiety will temporarily affect the physicochemical properties of the drug for increasing
their usefulness or decreasing ...
واقع أنشطة اللجنة الوطنية للمخيمات الصيفية في فلسطين لإكساب الأطفال المهارات الحياتية لعام (2011-2012)The Reality of the Activities of the National Committee for Palestinian Summer Camps (2011-2012
(AL-Quds Universityجامعة القدس, 2016-01-10)
This study was aimed to identify the reality of the activities of the National Committee
for Palestinian Summer Camps, In terms of making children acquire life skills for the
year 2011-2012. These skills are (contact and ...