Now showing items 1-3 of 3
Design, Synthesis, Characterization and In-Vitro Kinetic Study of Novel Antibacterials Prodrugs
(WJPR,Tara Pal,WJPR, 2015-10-30)
A number of marketed antibacterial drugs suffer several problems, such as bitter sensation and low stability which lead to patient incompliance. The prodrug approach is considered the most promising and extremely exciting ...
Computer-assisted design for atenolol prodrugs for the use in aqueous formulations
Based on stability studies on the drugs atenolol and propranolol and some of their derivatives it is believed that increasing the lipophilicity of the drug will lead to an increase in the stability of its aqueous solutions ...
Computer-Assisted Design for Paracetamol Masking Bitter Taste Prodrugs
It is believed that the bitter taste of paracetamol, a pain killer drug, is due to its hydroxyl group. Hence, it is expected that blocking the hydroxy group with a suitable linker could inhibit the interaction of ...