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Design, Synthesis and In-vitro Kinetic Study of Atovaquone Prodrug for the Treatment of Malaria
(WJPR,Tara Pal,WJPR, 2015-09-23)
Using DFT molecular orbital at B3LYP 6-31G (d,p) and
B3LYP/311+G (d,p) levels and molecular mechanics (MM2)
calculations of the hydrolysis of Bruice’s di-carboxylic semi-esters 1–5
several atovaquone prodrugs were ...
Depression Impairs Learning, whereas the Selective Serotonin Reuptake Inhibitor, Paroxetine, Impairs Generalization in Patients with Major Depressive Disorder
(Elsevier, 2014-11-01)
To better understand how medication status and task demands affect cognition in Major
Depressive Disorder (MDD), we evaluated medication-naïve patients with MDD, medicated
patients with MDD receiving the Selective Serotonin ...
Design, Synthesis, Characterization and In-Vitro Kinetic Study of Novel Antibacterials Prodrugs
(WJPR,Tara Pal,WJPR, 2015-10-30)
A number of marketed antibacterial drugs suffer several problems,
such as bitter sensation and low stability which lead to patient
incompliance. The prodrug approach is considered the most promising
and extremely exciting ...
Computer-assisted design for atenolol prodrugs for the use in aqueous formulations
(Springer-Verlag, 2011-07-23)
Based on stability studies on the drugs atenolol
and propranolol and some of their derivatives it is believed
that increasing the lipophilicity of the drug will lead to an
increase in the stability of its aqueous solutions ...
Anti-cancer Prodrugs-Three Decades of Design
(2015-07-31)
The conventional old treatment method for cancer therapy is associated with severe side effects along with several limitations. Therefore, searching and developing new methods for cancer became crucial. This mini review ...
Cost-utility analysis of a pharmacy-led self-management programme for patients with COPD
(Springer Science+Business Media B.V. 2011, 2011-06-04)
Objective: To undertake a cost-utility analysis
(CUA) of a pharmacy-led self-management programme for
Chronic Obstructive Pulmonary Disease (COPD). Setting:
A single outpatient COPD clinic at the Mater Hospital,
Belfast, ...
Degree of the Teachers’ Practice of Their Roles and Knowledge Economy Concepts from Their Perspective in Palestine
(2016-10-31)
This study aims at identifying the degree to which teachers are practicing their roles and knowledge economy concepts from their perspective in Palestine. Which raises teachers’ efficiency and improves their performance ...
Consanguineous Marriage and Its Effect on Offspring Congenital Malformation: A Study among Palestinian Rural Community
(Ivyspring International Publisher, 2016-08-03)
Objective: Consanguineous marriage is a long-standing socially accepted practice among Palestinian population. It is proposed
that consanguineous marriages increase the risk of congenital malformations and genetic disorders. ...
Depletive Water Balance and High Vulnerability Due to Conflicts over Access and Rights
(Scientific Research, 2014-08-03)
Sustainable water supply problem becomes strategic when inelastic demand levels are overhauling
maximum available supplies. The situation is more acute when the groundwater recharge area
is heavily populated, consist of ...
Data Integrity Mechanism Using Hashing Verification
(2014-09-20)
In this paper, we propose a new One-Way Hash Algorithm, which is also obtains better efficiency and security, compared with a particular conventional hash algorithm, Hash algorithm can be used to determine if two values ...