Phenolic and Flavonoids Analysis of Pomegranate Peel Extracts and their Antiniflammatory and Antioxidant Activities

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dc.contributor.authorK, Qabaha
dc.contributor.authorF, Al-Rimawi
dc.contributor.authorS, Nusseibeh
dc.contributor.authorJ, Abbadi
dc.contributor.authorS, Abu-Lafi
dc.date.accessioned2019-11-30T12:03:11Z
dc.date.available2019-11-30T12:03:11Z
dc.date.issued2019-03-25
dc.description.abstractAn in-vitro evaluation of the anti-inflammatory and antioxidant activities of pomegranate peel extract from Palestine were investigated. In parallel, the total phenolic content (TPC) and the total flavonoids content (TFC) were measured. The antioxidant activities were determined spectrophotometrically by DPPH, FRAP, CUPRAC and the ABTS methods. The phenolic and flavonoid contents were separated and partially identified using HPLC and LC-MS. In-vitro inhibitory effect of the extract on production of Interlukin-6 (Il-6) and Tumor Necrosis Factor-α (TNF-α) by Lipopolysacaride (LPS)-induced polymorphonuclear Cells (PMNCs) was evaluated. Pomegranate peel extract was found to have strong antiinflamatory activity as revealed by the reduction in the levels of IL-6 and TNF-alfa. It was also found that it is rich in phenoloic and flavonoids that enhanced its reducing activity and free radical scavenging ability.en_US
dc.identifier.citationInternational Journal of Pharmaceutical Quality Assuranceen_US
dc.identifier.issn0975 9506
dc.identifier.urihttps://dspace.alquds.edu/handle/20.500.12213/4974
dc.language.isoenen_US
dc.subjectPomegranate peelen_US
dc.subjectextracten_US
dc.subjectanti-inflammatoryen_US
dc.subjectantioxidant activityen_US
dc.subjectPhenolic compoundsen_US
dc.subjectflavonoidsen_US
dc.titlePhenolic and Flavonoids Analysis of Pomegranate Peel Extracts and their Antiniflammatory and Antioxidant Activitiesen_US
dc.typeBooken_US
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